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Table 5 Mexican launch dates of drugs used to treat different types of cancer

From: The impact of pharmaceutical innovation on cancer mortality in Mexico, 2003–2013

Cancer site

Drug

Launch year

C00–C14 head and neck cancer

Docetaxel

1995

C00–C14 head and neck cancer

Cetuximab

2004

C15 esophageal cancer

Docetaxel

1995

C15 esophageal cancer

Trastuzumab

2000

C16 stomach (gastric) cancer

Docetaxel

1995

C16 stomach (gastric) cancer

Trastuzumab

2000

C18, C20 colon and rectal cancer

Irinotecan

1998

C18, C20 colon and rectal cancer

Capecitabine

2000

C18, C20 colon and rectal cancer

Oxaliplatin

2002

C18, C20 colon and rectal cancer

Cetuximab

2004

C18, C20 colon and rectal cancer

Bevacizumab

2005

C18, C20 colon and rectal cancer

Panitumumab

2011

C18, C20 colon and rectal cancer

Aflibercept

2014

C25 pancreatic cancer

Paclitaxel

1995

C25 pancreatic cancer

Gemcitabine

1997

C25 pancreatic cancer

Irinotecan

1998

C25 pancreatic cancer

Erlotinib

2006

C25 pancreatic cancer

Everolimus

2006

C25 pancreatic cancer

Sunitinib

2006

C34 lung cancer

Carboplatin

1992

C34 lung cancer

Docetaxel

1995

C34 lung cancer

Paclitaxel

1995

C34 lung cancer

Gemcitabine

1997

C34 lung cancer

Vinorelbine

1998

C34 lung cancer

Gefitinib

2004

C34 lung cancer

Bevacizumab

2005

C34 lung cancer

Pemetrexed

2005

C34 lung cancer

Erlotinib

2006

C34 lung cancer

Topotecan

2008

C34 lung cancer

Crizotinib

2012

C40–C41 bone cancer

Denosumab

2012

C43 melanoma

Interferon alfa-2b

1987

C43 melanoma

Aldesleukin

1996

C43 melanoma

Peginterferon alfa-2b

2001

C43 melanoma

Ipilimumab

2012

C43 melanoma

Vemurafenib

2012

C44 basal cell carcinoma

Imiquimod

1999

C45 malignant mesothelioma

Pemetrexed

2005

C46 kaposi sarcoma

Interferon alfa-2b

1987

C46 kaposi sarcoma

Paclitaxel

1995

C49 soft tissue sarcoma

Imatinib

2001

C49 soft tissue sarcoma

Trabectedin

2010

C49 soft tissue sarcoma

Pazopanib

2012

C50 breast cancer

Epirubicin

1987

C50 breast cancer

Goserelin

1991

C50 breast cancer

Docetaxel

1995

C50 breast cancer

Paclitaxel

1995

C50 breast cancer

Gemcitabine

1997

C50 breast cancer

Anastrozole

1998

C50 breast cancer

Raloxifene

1998

C50 breast cancer

Toremifene

1999

C50 breast cancer

Capecitabine

2000

C50 breast cancer

Letrozole

2000

C50 breast cancer

Trastuzumab

2000

C50 breast cancer

Exemestane

2004

C50 breast cancer

Everolimus

2006

C50 breast cancer

Fulvestrant

2009

C50 breast cancer

Ixabepilone

2009

C50 breast cancer

Lapatinib

2009

C50 breast cancer

Trastuzumab emtansine

2014

C53 cervical cancer

Bevacizumab

2005

C53 cervical cancer

Topotecan

2008

C56 ovarian, fallopian tube, or primary peritoneal cancer

Carboplatin

1992

C56 ovarian, fallopian tube, or primary peritoneal cancer

Paclitaxel

1995

C56 ovarian, fallopian tube, or primary peritoneal cancer

Gemcitabine

1997

C56 ovarian, fallopian tube, or primary peritoneal cancer

Bevacizumab

2005

C56 ovarian, fallopian tube, or primary peritoneal cancer

Topotecan

2008

C61 prostate cancer

Flutamide

1987

C61 prostate cancer

Mitoxantrone

1987

C61 prostate cancer

Leuprorelin

1989

C61 prostate cancer

Goserelin

1991

C61 prostate cancer

Docetaxel

1995

C61 prostate cancer

Bicalutamide

1997

C61 prostate cancer

Degarelix

2010

C61 prostate cancer

Cabazitaxel

2012

C64–C65 kidney (renal cell) cancer

Aldesleukin

1996

C64–C65 kidney (renal cell) cancer

Bevacizumab

2005

C64–C65 kidney (renal cell) cancer

Everolimus

2006

C64–C65 kidney (renal cell) cancer

Sunitinib

2006

C64–C65 kidney (renal cell) cancer

Temsirolimus

2011

C64–C65 kidney (renal cell) cancer

Pazopanib

2012

C71 brain tumors

Temozolomide

1999

C71 brain tumors

Bevacizumab

2005

C71 brain tumors

Everolimus

2006

C73 thyroid cancer

Vandetanib

2014

C81 hodgkin lymphoma

Brentuximab vedotin

2014

C82–C85 non-hodgkin lymphoma

Interferon alfa-2b

1987

C82–C85 non-hodgkin lymphoma

Rituximab

1999

C82–C85 non-hodgkin lymphoma

Bortezomib

2006

C82–C85 non-hodgkin lymphoma

Lenalidomide

2008

C82–C85 non-hodgkin lymphoma

Plerixafor

2009

C82–C85 non-hodgkin lymphoma

Brentuximab vedotin

2014

C90 multiple myeloma and other plasma cell neoplasms

Zoledronic acid

2001

C90 multiple myeloma and other plasma cell neoplasms

Bortezomib

2006

C90 multiple myeloma and other plasma cell neoplasms

Lenalidomide

2008

C90 multiple myeloma and other plasma cell neoplasms

Plerixafor

2009

C91, C92 leukemia

Interferon alfa-2b

1987

C91, C92 leukemia

Mitoxantrone

1987

C91, C92 leukemia

Idarubicin

1992

C91, C92 leukemia

Rituximab

1999

C91, C92 leukemia

Imatinib

2001

C91, C92 leukemia

Dasatinib

2007

C91, C92 leukemia

Nilotinib

2007

C91, C92 leukemia

Clofarabine

2009

C91, C92 leukemia

Obinutuzumab

2014